Is Vegetable Really Good for Diabetics?

According to World Health Organization (WHO), diabetes affects more than 285 millions people worldwide, of which 4 million people of them will die every year by 2010. The number could rise up to 438 millions by 2030 with the increasing obesity rate.

Type 2 diabetes, being the commonest form of diabetes, has swiftly spread from wealthy to the fast-developing countries because of the fatty, sugary diets and sedentary lifestyles.

While nutrition and exercise are important in the prevention of such disease, the dispute on ‘which foods work best and why’ continues. This is because only few good quality studies were carried out to explore such issue.

Recently, researchers from the University of Leicester, central England found that eating more spinach and other green leafy vegetables could actually reduce the risk of Type-2 diabetes. Their findings were published in the British Medical Journal (BMJ) on August 20, 2010.

6 studies involving 220,000 people were reviewed to explore the link between fruit and vegetable consumption and Type-2 diabetes. The results showed that eating one and a half extra servings (106 gm) of green leafy vegetables reduce the risk of diabetes by 14 percent, while eating more fruit and vegetables combined had negligible impact.

Researchers could not explain why leafy vegetables have such protective effect, though they suspected it is probably because of the high antioxidants such as Vitamin C and magnesium found in green leafy vegetables.

As such, they suggested more investigation should be carried out to confirm their findings. Other health experts also felt that it was too early to isolate green leafy vegetables and regard them alone as a way to reduce the risk of getting Type-2 diabetes.

Meanwhile, the researchers as well as other experts in the field urged people to continue consuming 5 portions of fruit and vegetables a day, which would benefit people in the prevention heart disease, stroke, some cancers and obesity as well as Type-2 diabetes.

The National Diet Nutrition Survey showed that, although fruit and vegetable intake has increased over the past decade, only a third of men and women eat the recommended five-a-day in 2008/09.

Would Vitamin Help Diabetics?

For people who are unable to get adequate amount of vitamins and minerals from their diet, taking vitamin supplements could be a feasible alternative to help them meet their nutrition requirements. The elderly, strict vegetarians, people on low-calorie diets and those that are malnourished are some good examples of this type of people.

How about diabetics? Would vitamin help control their condition? Most health organizations associated with diabetes do not advocate using vitamins. In fact, they usually warn against using large doses of vitamins or supplements, which could possibly cause adverse side effects.

In April 28, 2010 edition of the Journal of the American Medical Association (JAMA), researchers from the University of Western Ontario and the Robarts Research Institute in London, Ontario reported that patients with diabetic nephropathy would suffer rapid deterioration of the kidneys if treated with high doses of Vitamin B. Moreover, these patients are likely to face a higher risk of heart attack and stroke than patients who took a placebo.

Diabetic nephropathy is a progressive kidney disease because of longstanding diabetes mellitus, and it is a prime indication for dialysis in many Western countries. Even with the many treatments available right now, about 40 percent of the 21 million Americans who have diabetes still develop diabetic nephropathy.

Prior observational studies have shown that there is an association between high concentrations of plasma total homocysteine and the risk of developing diabetic nephropathy, retinopathy, and vascular diseases, including myocardial infarction and stroke. B-Vitamin therapy using folic acid, Vitamin-B6 and Vitamin-B12 is known to be capable of lowering the plasma concentration of homocysteine.

With an aim to developing a new approach to treatment, the researchers conducted a study to see if B-Vitamin therapy would actually slow progression of diabetic nephropathy and prevent vascular events in 238 patients with Type-1 or Type-2 diabetes. Meanwhile, the placebo-controlled trial was carried out at 5 university medical centers in Canada between May 2001 and July 2007.

Patients were prescribed with single tablet of B-Vitamins with folic acid (2.5 mg/d), Vitamin-B6 (25 mg/d), and Vitamin-B12 (1 mg/d), or matching placebo. After an average period of 31.9 months, patients with Vitamin-B were found to have a faster rate of reduction of kidney filtering and so the kidney function, as compared with those on a placebo course. For patients with the diabetic nephropathy, the risk of heart attack and stroke were also higher than those who took placebo.

Skinny-Thigh Could Cause Heart Disease

Overweight or obesity has been shown by earlier studies to be one of the many risk factors, like diabetes, smoking, hypertension, and high cholesterol, of heart disease.

A study appeared in the British Medical Journal (BMJ) on September 4, 2009 reported that women and men with thighs smaller than 60 cm (or about 23.6 inches) in circumference would face a much higher risk of premature death and heart disease. It is believed that this is the very first to examine the implications of thigh size on heart disease.

Danish researchers from Copenhagen University Hospital looked at data obtained from 1,436 men and 1,380 women. The body measurements of these participants were taken in Demark in the late 1980s. Over the next 12 years, more than 400 participants died and another 540 suffered either cardiovascular or heart disease, and the ratio of men to women was roughly 2 to 1.

The findings showed that survivors without any heart disease had significantly thicker thighs, after taking into account of other risk factors of heart disease. People with thigh size smaller than 60 cm had a much higher risk of premature death.

Nevertheless, 60 cm was the threshold. This means that larger (than 60 cm) thigh size did not seem to offer any additional benefit for either sex. In fact, those with the thinnest thighs (less than 18 inches around) were more than 3 times more likely to die compared with those with the 60-cm thighs, and more than twice as likely to have heart disease.

It is possible that, according to researchers, a lack of lower body muscle mass could affect a proper glucose and lipid metabolism, which in turn put the body at risk of developing disease. As such, they proposed further study to find out the reasons.

Meanwhile, suggestion by the researchers to use thigh size for assessing heart disease risks together with other measures like body mass index (BMI) and waist and hip circumference met objection from some health experts. The opposers doubted that the thigh size could be clinically useful.

What Else Can Cause Obesity?

While many studies have blamed the increasingly sedentary lifestyle and the availability of low-cost high-calorie foods to be the culprit for obesity epidemic in the developed countries, there might be other reasons behind this.

Researchers from Emory University School of Medicine and the University of Colorado at Boulder found that the bugs that help digest food could also cause the body to gain weight if they are not properly regulated. If wrong kinds of bacteria were dominant, they could cause a low-level inflammation leading to a pre-diabetic condition and an elevated appetite, as explained in a paper published on March 4, 2010 in the Journal “Science”.

In the study, researchers examined mice that were genetically engineered to be deficient in a key immune system protein, namely TLR5, which helps cells sense the presence of bacteria. Such protein plays an important role in the intestinal community, meaning it knows not to apply too much force and does not harm the good bacteria.

In the absence of TLR5, the immune system can still regulate bacteria but it just could not do it properly. When the bacterial composition changes, a low level inflammation sets in and insulin receptors are desensitized.

To justify the theory, a series of experiments were preformed on mice. The results showed that if the TLR5-deficient mice were given unrestricted diets, they ate 10 percent more and gained 20 percent more weight than the normal mice. Even if their food was limited, the TLR5-deficient mice were still less sensitive to insulin than the normal mice.

The TLR5-deficient mice also developed metabolic syndrome, which could cause weight gain, high blood pressure and high cholesterol levels, and it could raise the risk for developing diabetes and heart disease.

While the study was limited to mice, experts still believe they might applicable to humans as well. The findings suggested that excess caloric consumption is not only the result of undisciplined eating style but also changes in appetite and metabolism caused by the intestinal bacteria.

It Is Not Too Difficult To Prevent Hypertension!

Hypertension, or more commonly known as high blood pressure, is the second-leading cause of death in the United States. It usually has no symptoms but it can lead to development of many complications including heart disease, kidney failure and stroke, if the condition is not controlled. Many people can have hypertension for years even without knowing it.

Yet, hypertension is regarded as a “neglected disease”! This is what a report, commissioned by the United States Centers for Disease Control and Prevention (CDC) and published on February 22, 2010 in the Institute of Medicine, suggested.

The report showed that nearly one-third of the American adults have hypertension, and the number is on the rise. Every year, hypertension also accounts for about one-sixth of adult deaths, which is a 25 percent increase from 1995 to 2005.

The prevailing measures for hypertension prevention is definitely inadequate: doctors do not treat it aggressively and governments have not sufficiently prioritized their task. But the report stressed that prevent and treat hypertension is not difficult at all. Some means that would help manage and even prevent hypertension were outlined in the report.

The first priority is to cut the salt intake. It is estimated that some 80 percent of Americans are consuming more than the recommended amount of salt and the number is increasing! As some 70 percent of Americans had their sodium (salt) intake from package foods and restaurants, and not from their family meals, it is important for the food industry to manufacture and supply foods that contain less salt to the public.

Health experts are required to do their part, too. It is known that only one-third of people who have hypertension have the condition controlled. Many people who either are not aware that hypertension has struck them or have hypertensive condition not appropriately controlled by the health care providers who have diagnosed it.

Effort should be made to break the economic barriers that prevent patients from taking their medication. It is recommended that CDC need to work closely with various relevant parties to help hypertensive patients who need the medications.

Besides cutting salt, people should also eat more potassium, get some exercise and lose some weight. These steps would surely make a big difference in how many people suffer hypertension.

Be Happy for Heart Disease Prevention!

There are about 2.5 million people in Britain with heart disease, which is the single biggest killer, causing 94,000 deaths a year.

While “do not smoke, have a healthy diet and exercise regularly” are the 3 basic things that people could do to maintain a healthy heart and avoid heart attack, a paper published online on February 18, 2010 in the European Heart Journal indicated that happiness might help to keep a healthy heart!

Researchers from Columbia University Medical Centre in New York, America used a 5-point scale to measure happiness levels of more than 1,700 adults in Canada with no heart disease in 1995. After a decade, they examined the 145 people who developed heart disease and found that happier people were less likely to have had heart problem.

After statistically adjusting to account for other factors like age, gender and smoking, it was found that for every point on the happiness scale, people were 22 percent less likely to develop heart disease.

It has been known that depression and stress would significantly raise people’s risk of developing heart disease, but this study is believed to be the first to suggest happiness could lessen heart disease risk.

Happy people tend to be more likely to have a healthier lifestyle. This could be owing to an unknown genetic trait embedded in these people making them happy and have less heart disease.

According to researchers, even if one is not naturally a happy person, just try acting like one; it could really help the heart!

Ordinary people can ensure they engage with some activities that they like in their daily lives. For example, spending 15 minutes or so to read a book or incorporate activities like walking or listening to music in the daily schedule if these activities could improve one’s mood.

Nevertheless, as this study used an experimental design that is good for observation of trends and associations, it does not prove cause and effect nor confirm lowering risk of heart disease by changing one’s mood. Perhaps, more studies should be carried out to find out more from the cause and effect perspective.

Why A High-Fat Diet Should Be Avoided?

People are usually advised not to have high-fat diet, as this would very likely make people become overweight or even obese. At the same time, it would increase the chance of developing many diseases including heart disease, high blood pressure, and stroke.

A study, believed to be the largest to look at stroke risk in women and across all types of fat, revealed that eating a high-fat diet especially trans fats, could raise the risk for ischemic stroke in postmenopausal women. Ischemia stoke is the most common type of stoke caused clogged blood vessels supplying the brain.

Women who aged 55 and above and ate the most total fat, including monounsaturated and polyunsaturated fats as well as trans and saturated fats, had a 44 percent higher risk of ischemic stroke, as compared to those who ate the least. Meanwhile, women who consumed the highest amount of trans fat had a 30 percent more likely to get ischemic stroke, compared with those who consumed the least.

Researchers from the University of North Carolina, Chapel Hill presented their findings on February 24, 2010 at the American Stroke Association International Stroke Conference 2010.

Previous studies had linked trans fat to the development of coronary heart disease, but studies on the association of ischemic stroke and fat have been inconclusive.

87,230 participants in the Women's Health Initiative, which is a federally funded study for revealing health risks from taking hormone pills for menopause symptoms, were involved. Participants, between the age of 50 and 79, were asked to fill out detailed surveys on their diets when they enrolled. They were divided into 4 groups based on how much fat they ate, and were followed for an average of 7.6 years to see how many had suffered ischemia stroke. A total of 1049 ischemic strokes were found among the women.

It has been known that postmenopausal women would face a higher risk of ischemic stroke than men of the same age. Before menopause, women have a lower risk of stroke than men of similar age. Nevertheless, their risk doubles every 10 years after the age of 55.